Preheat the oven to 375°F (190°C). Grease a 9x13 inch baking dish with nonstick cooking spray.
In a large skillet over medium-high heat, brown the ground beef, breaking into small crumbles. Drain off any excess grease.
Add the marinara sauce to the ground beef and simmer for 1-2 minutes until the mixture is thickened and not runny. Set aside.
Separate the 8 biscuits and use your fingers to press them into 4-inch circles.
Spoon about 1 tablespoon of the ground beef mixture into the center of each circle and top with a generous amount of mozzarella cheese.
Bring the sides of the dough up and over the filling and pinch to seal.
Place the stuffed dough balls into the baking dish seam side down. Leave a little space between each ball.
In a small bowl, combine the melted butter, garlic powder, and dried oregano. Brush the garlic butter over the tops of the dough balls.
Bake for 15-17 minutes until golden brown and puffy. Top with fresh parsley and serve with extra marinara sauce for dipping.